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KMID : 1225720140060030196
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Allergy, Asthma & Immunology Research : AAIR
2014 Volume.6 No. 3 p.196 ~ p.200
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Current Status of Standardization of Inhalant Allergen Extracts in Korea
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Jeong Kyoung-Yong
Lee Jae-Hyun
Kim Eun-Jin
Lee Joo-Shil
Cho Sang-Heon
Hong Soo-Jong
Park Jung-Won
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Abstract
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Allergy diagnosis and immunotherapy in Korea rely mostly on imported allergen extracts. However, some allergens that are not important in Western countries are not commercially available, and even the same species of allergen source often displays differences in allergenicity due to amino acid sequence polymorphisms. Therefore, it is essential to prepare allergen extracts that reflect regional characteristics. Allergen standardization has been performed since 2009 with the support of the Korea Center for Disease Control and Prevention. Here, we summarize the current status of allergen standardization, focusing on the house dust mite and cockroach. Pollen allergens that are under investigation are also briefly described.
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KEYWORD
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Allergen, allergen extract, standardization
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